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Antihistamine


Source: https://upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Histamine.svg/50px-Histamine.svg.png

Description. Lang: en

Antihistamines are drugs which treat allergic rhinitis and other allergies.  Typically people take antihistamines as an inexpensive, generic, over-the-counter drug that can provide relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. Antihistamines are usually for short-term treatment. Chronic allergies increase the risk of health problems which antihistamines might not treat, including asthma, sinusitis, and lower respiratory tract infection. Consultation of a medical professional is recommended for those who intend to take antihistamines for longer-term use.Although people typically use the word “antihistamine” to describe drugs for treating allergies, doctors and scientists use the term to describe a class of drug that opposes the activity of histamine receptors in the body. In this sense of the word, antihistamines are subclassified according to the histamine receptor that they act upon. The two largest classes of antihistamines are H1-antihistamines and H2-antihistamines.
H1-antihistamines work by binding to histamine H1 receptors in mast cells, smooth muscle, and endothelium in the body as well as in the tuberomammillary nucleus in the brain. Antihistamines that target the histamine H1-receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing). In addition, they may be used to treat insomnia, motion sickness, or vertigo caused by problems with the inner ear. H2-antihistamines bind to histamine H2 receptors in the upper gastrointestinal tract, primarily in the stomach. Antihistamines that target the histamine H2-receptor are used to treat gastric acid conditions (e.g., peptic ulcers and acid reflux).
Histamine receptors exhibit constitutive activity, so antihistamines can function as either a neutral receptor antagonist or an inverse agonist at histamine receptors. Only a few currently marketed H1-antihistamines are known to function as inverse agonists.
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Antihistamine

Antihistamine

Drug class

  • Desc: Antihistamines are drugs which treat allergic rhinitis and other allergies. Typically people take antihistamines as an inexpensive, generic, over-the-counter drug that can provide relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects.
  • Wiki: https://en.wikipedia.org/wiki/Antihistamine
  • Type: Thing
  • Result Score: 6615.87

H1 antagonist

Drug class

  • Desc: H₁ antagonists, also called H₁ blockers, are a class of medications that block the action of histamine at the H₁ receptor, helping to relieve allergic reactions.
  • Wiki: https://en.wikipedia.org/wiki/H1_antagonist
  • Type: Thing
  • Result Score: 787.67

Antihistamine

Song by Tricky

  • Type: Thing, MusicRecording
  • Result Score: 7.00

Antihistamine

Song by Tricky

  • Type: Thing
  • Result Score: 7.00

Eye decongestant / Antihistamine

Drug class

  • Type: Thing
  • Result Score: 2.14
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